2-Bromo-1, 3-dimethylbenzene is inert to nucleophilic aromatic substitution on treatment with sodium amide in liquid ammonia. It

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2-Bromo-1, 3-dimethylbenzene is inert to nucleophilic aromatic substitution on treatment with sodium amide in liquid ammonia. It is recovered unchanged even after extended contact with the reagent. Suggest an explanation for this lack of reactivity.

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Organic Chemistry

ISBN: 978-0072905014

4th edition

Authors: Francis A. Carey

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Question Posted: Dec 26, 2009 01:03 AM

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2-Bromo-1, 3-dimethylbenzene is inert to nucleophilic aromatic substitution on treatment with sodium amide in liquid ammonia. It

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The aryl halide is incapable of elimination and ...View the full answer

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