2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as the Fischer indole

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2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as the Fischer indole synthesis. Propose a mechanism for this reaction. (Hint: The reactive species is the enamine tautomer of the phenylhydrazone.)

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Organic Chemistry

ISBN: 978-0131407480

4th edition

Authors: Paula Yurkanis Bruice

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Question Posted: Jun 10, 2016 07:28 AM

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2-Phenylindole is prepared from the reaction of acetophenone and phenylhydrazine, a method known as the Fischer indole

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Ht CCH3 + + NH3 + H20

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CH3 NHNH OCCHs CH3 T NHNCCHs C6H ...View the full answer

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