A tert-l3utyI esters [RCO2C (CH3)3] are converted into carboxylic acids (RCO2H) by reaction with trifluoroacetic acid, a reaction useful in protein synthesis (Section 26.7). Assign E, Z designation to the double bonds of both reactant and product in the following scheme, and explain why there is an apparent change of double-bonds tereochemistry:

Transcribed Image Text:

с-оснз С-оснз НаС%3DCICH3)2 CF3CO2H Нас С-Он Нас -oc(CH3)3