Briefly describe the biological rationale for each of the following allosteric phenomena: (a) Activation of pyruvate carboxylase
Question:
(a) Activation of pyruvate carboxylase by acetyl-CoA;
(b) Activation of pyruvate dehydrogenase kinase by NADH;
(c) Inhibition of isocitrate dehydrogenase by NADH;
(d) Activation of isocitrate dehydrogenase by ADP;
(e) Inhibition of a-ketoglutarate dehydrogenase by succinyl-CoA;
(f) Activation of pyruvate dehydrogenase phosphatase by Ca2+.
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Related Book For
Biochemistry Concepts and Connections
ISBN: 978-0321839923
1st edition
Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews
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