Chloramphenicol (at right) is a potent antibiotic, isolated from Streptomyces venezuelae, that is particularly effective against typhoid

Question:

Chloramphenicol (at right) is a potent antibiotic, isolated from Streptomyces venezuelae, that is particularly effective against typhoid fever. It was the first naturally occurring substance shown to contain a nitro (-NO2) group attached to an aromatic ring. Both chirality centers in chloramphenicol are known to have the (R) configuration. Identify the two chirality centers and write a three-dimensional formula for chloramphenicol.