Question: Explain why inserting 5 bp of DNA at the -50 position of a eukaryotic gene decreases the rate of RNA polymerase II transcription initiation to

Explain why inserting 5 bp of DNA at the -50 position of a eukaryotic gene decreases the rate of RNA polymerase II transcription initiation to a greater extent than inserting 10 bp at the same site.

Step by Step Solution

★★★★★

3.46 Rating (172 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

Promoter elements for RNA polymerase II include sequ... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Document Format (1 attachment)

930-M-S-B-C (1782).docx

120 KBs Word File

Students Have Also Explored These Related Biochemistry Questions!

Explain why a DNA polymerase that could synthesize DNA in the 3' 5' direction would have a selective disadvantage even if it had 5' 3' proofreading activity.

DNA isolated from an organism can be sheared into fragments of uniform size (1000 bp), heated to separate the strands, then cooled to allow complementary strands to reanneal. The renaturation process...

The technique of DNA footprinting is described in Chapter 20. If a protein binds over a region of DNA, it will protect the DNA in that region from digestion by DNase I. To carry out a DNA...

Can anyone solve the answers from the given document givenbelow? I really need help. MY FINAL LITERALLY IS KNOCKING AT THE DOOR. Name_________________________________ Student...

Examine the pricing strategies in the gasoline market. Make sure to address the following topics: In the article, (Mixed) Strategy in Oligopoly Pricing: Evidence from Gasoline Price Cycles Before and...

SOMEONE PLEASE HELP ME GIVE ALL THE ANSWERS!!!!! MY EXAM IS ON 13th MORNING! SO PLEASEEEEE!!!!! 2. An investment is expected to pay the following: C 1 = $2,300, C 2 = $2,600, C 3 = $2,900, and then...

1. A bank is paying interest at a 5% annual rate on deposits. If you invest 10,000 and the bank compounds interest daily (i.e., 365 times per year), which of the following shows how much you will...

please solve all the questions. reference https://studylib.net/doc/5560557/management-control-in-decentralized-organizations...

please help with questions 22,23,24, and 27 500 APPENDIX B Muffler Magic really have an incentive pay poblem, or were the problems more broad? Furthermoge, how, if at all, would the professor's...

solve all question . reference ; https://studylib.net/doc/5560557/management-control-in-decentralized-organizations...

Why must the user be cautious in analyzing bank holding companies?

Calculate the percentage of chalorine (35.453g/mol) in a swimming pool chlorinating agent that is 99.4% trichloro triazine C 3 Cl 3 N 3 (184.412g/mol)

15. Challenge: Using only SUB, MOV, and AND instructions, show how to calculate x = n mod y, assuming that you are given the values of n and y. You can assume that n is any 32-bit unsigned integer,...

Overheating is a major problem in microprocessor operation. After much testing, it has been determined that the operating temperature is normally distributed with a mean of 150 degrees and a standard...

The hydrolysis of a phenylalanine-containing peptide is catalyzed by a-chymotrypsin with the following results. Calculate KM and Vmax for the reaction. Peptide Concentration (M)Velocity (M min-1) 2.5...

Why is it useful to plot rate data for enzymatic reactions as a straight line rather than as a curve?

How do the KM values for glucoki-nase and hexokinase reflect their roles in sugar metabolism?

Calls Puts Strike Close Price Expiration Vol. Last Vol. Last Hendreeks 103 100 Feb 72 5.20 50 2.40 103 100 Mar 41 8.40 29 4.90 103 100 Apr 16 10.68 10 6.60 103 100 Jul 8 14.30 2 10.10 Suppose you buy...

ellook Wandering RV is evaluating a capital budgeting project that is expected to generate $30,650 per year during its seven-year life. If its required rate of return is 14 percent, what is the value...

CVP Analysis of Multiple Products Steinberg Company produces commercial printers. One is the regular model, a basic model that is designed to copy and print in black and white. Another model, the...