Figure 8.19 shows a proposed mechanism for carboxypeptidase A. In Figure 8.19 a. What is the role

Question:

Figure 8.19 shows a proposed mechanism for carboxypeptidase A.
In Figure 8.19

a. What is the role of Glu 270 in catalysis?
b. What is the role of Arg 145 in catalysis?

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Biochemistry Concepts and Connections

ISBN: 978-0321839923

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Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews

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Question Posted: Apr 21, 2016 04:15 AM

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Figure 8.19 shows a proposed mechanism for carboxypeptidase A. In Figure 8.19 a. What is the role

Question:

Bond cleavage NH (R145) 0 Rn (H69) (E72) (H196) (E270) (R145 (H69) (E72) (H196) (E270) (R145 (H69) (E72) (H196) (E270) Release products and bind water

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a E270 acts as a GBC general base catalyst in step one an...View the full answer

Biochemistry Concepts and Connections

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