Signaling molecules interact with cells through specic macromolecular receptors. For each of the four receptors identied below,

Signaling molecules interact with cells through specific macromolecular receptors. For each of the four receptors identified below, list all characteris-tics, by number, which accurately describe that receptor.
(a) An adrenergic receptor ________
(b) A steroid receptor ____________
(c) Te LDL receptor _____________
(d) Te insulin receptor ___________
(1) Located at the cell surface
(2) Associated with the protein clathrin
(3) Ligand binding stimulates the activity of phospholipase C
(4) A transmembrane protein
(5) A DNA-binding protein
(6) Located in the cell interior
(7) Receptor-ligand complex moves to the lysosome
(8) Receptor-ligand complex becomes concentrated in the nucleus
(9) Receptor activation can inhibit the synthesis of glycogen
(10) Te hormone-receptor complex activates specific gene transcription
(11) Internalization decreases the synthesis of cholesterol esters
(12) Action of this receptor diminishes the synthesis and activity of β-hydroxy-β-methylglutaryl-CoA reductase (HMG-CoA reductase)
(13) This receptor activates its own synthesis
(14) Biological activity of this receptor involves interaction with guanine nucleotide-binding proteins
(15) This receptor has a protein kinase activity
(16) Not known to act through a second messenger