64. The article Increases in Steroid Binding Globulins Induced by Tamoxifen in Patients with Carcinoma of the
Question:
64. The article “Increases in Steroid Binding Globulins Induced by Tamoxifen in Patients with Carcinoma of the Breast”
(J. Endocrinology, 1978: 219–226) reports data on the effects of the drug tamoxifen on change in the level of cortisolbinding globulin (CBG) of patients during treatment. With age x and CBG y, summary values are n 26, xi
1613, (xi x
)2 3756.96, yi 281.9, (yi y
)2
465.34, and xi yi 16,731.
a. Compute a 90% CI for the true correlation coefficient .
b. Test H0: .5 versus Ha: .5 at level .05.
c. In a regression analysis of y on x, what proportion of variation in change of cortisol-binding globulin level could be explained by variation in patient age within the sample?
d. If you decide to perform a regression analysis with age as the dependent variable, what proportion of variation in age is explainable by variation in CBG?
Step by Step Answer:
Probability And Statistics For Engineering And The Sciences
ISBN: 9781111802325
7th Edition
Authors: Dave Ellis, Jay L Devore