Lysine degradation requires removal of two amino groups. Removal of its e-amino group gives a-aminoadipic semialdehyde. This

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Lysine degradation requires removal of two amino groups. Removal of its e-amino group gives a-aminoadipic semialdehyde. This product is then degraded to acetoacetate by the same chemical strategy used to degrade the branched-chain amino acids. Draw the proposed intermediates in this pathway.

H 0=0 -5-8-8- CH CH CH H NH T COO a-Aminoadipic semialdehyde

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Biochemistry Concepts And Connections

ISBN: 9780134641621

2nd Edition

Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews

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