For the data in Table 7.15, suppose we wish to compare the difference in EORTC QLQ‐C30 physical function domain scores before and after exercise. Which ONE of the following statistical methods would be most appropriate to compare physical function scores before and after exercise?

A. Two independent samples t‐test B. Paired t‐test C. Mann–Whitney U test D. Chi‐squared test E. One‐way ANOVA

Table 7.15

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EORTC QLQ-C30 physical function scale score Subject (i) Before After 1 2 3 66.7 100.0 40.0 60.0 80.0 100.0 45 4 80.0 100.0 5 53.3 86.7 6 80.0 90.3 7 53.3 60.0 8 20.0 46.7 Mean 61.7 78.0