Question: A study considered the effect of prednisolone on severe hypercalcaemia in women with metastatic breast cancer (B. Kristensen et al., J. Intern. Med. 232: 237245,

A study considered the effect of prednisolone on severe hypercalcaemia in women with metastatic breast cancer (B. Kristensen et al., J. Intern. Med. 232: 237–245, 1992). Of 30 patients, 15 were randomly selected to receive prednisolone. The other 15 formed a control group. Normalization in their level of serum-ionized calcium was achieved by 7 of the treated patients and none of the control group. Analyze whether results were significantly better for treatment than for control. Interpret.

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