Gout resulting from the de novo overproduction of purines can be distinguished from gout caused by impaired

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Gout resulting from the de novo overproduction of purines can be distinguished from gout caused by impaired excretion of uric acid by feeding a patient 15N-labeled glycine and determining the distribution of 15N in his or her excreted uric acid. What isotopic distributions are expected for each type of defect?

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Fundamentals Of Biochemistry Life At The Molecular Level

ISBN: 9781118918401

5th Edition

Authors: Donald Voet, Judith G Voet, Charlotte W Pratt

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