Is the information in Problem 37 consistent with the hypothesis that dietary restriction can slow the aging
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Is the information in Problem 37 consistent with the hypothesis that dietary restriction can slow the aging process?
Problem 37
During dietary restriction, amino acids may be used as metabolic fuels. In this process, glutamate is converted by glutamate dehydrogenase to α-ketoglutarate. α-Ketoglutarate binds to the β subunit of ATP synthase and inhibits its catalytic activity. Predict the effect of increased α-ketoglutarate on oxygen consumption and the production of reactive oxygen species.
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Related Book For
Fundamentals Of Biochemistry Life At The Molecular Level
ISBN: 9781118918401
5th Edition
Authors: Donald Voet, Judith G Voet, Charlotte W Pratt
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