The compound you identified in Problem 9 resembles glutamate and might therefore competitively inhibit glutamate transamination. How
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The compound you identified in Problem 9 resembles glutamate and might therefore competitively inhibit glutamate transamination. How would this affect citric acid cycle activity?
Data from in problem 9
Some human brain cancer cells contain a mutated form of isocitrate dehydrogenase that has lost its normal activity and instead catalyzes the NADP+-dependent reduction of the carbonyl group of α-ketoglutarate. Draw the structure of the reaction product.
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The compound mentioned in Problem 9 that resembles glutamate and might competitively inhibit glutamate transamination is likely ketoglutarate If ketog...View the full answer
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Related Book For 
Fundamentals Of Biochemistry Life At The Molecular Level
ISBN: 9781118918401
5th Edition
Authors: Donald Voet, Judith G Voet, Charlotte W Pratt
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