1. Use linear-regression methods to assess whether plasma-carotene levels increase over the 12-week period. Use appropriate data transformations if necessary. Perform separate analyses for each of the four preparations?

2. Do you have any recommendations as to which preparation should be used in the main clinical trial?

Bioavailability

Refer to Table 12.35.

Table 12.35: Format of BETACAR.DAT

 

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Variable Column Code 1 = SOL; 2 = ROCHE; 3 = BASF-30; 4 = BASF-60 Preparation Subject number First baseline level Second baseline level Week 6 level Week 8 level Week 10 level 3-4 6-8 10-12 14-16 18-20 22-24 Week 12 level 26-28