How much power does this study have to detect a mean difference of 5 units in the
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How much power does this study have to detect a mean difference of 5 units in the symptom scale if a two-sided test is used with α = .05?
Neurology
In a 5-year follow-up of bilateral stimulation of the subthalamic nucleus among 49 patients with advanced Parkinson’s disease, investigators assessed changes in symptoms as measured by the Unified Parkinson’s Disease Rating Scale (range = 0 to 108, with higher values denoting more symptoms). Assume this measure follows a normal distribution. The mean score at baseline was 55.7. The standard deviation of change from baseline to 5 years was 15.3.
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