Suppose we conduct a study of the preceding hypothesis based on 20 participants. What is the probability
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Suppose we conduct a study of the preceding hypothesis based on 20 participants. What is the probability we will be able to reject H0 using a one-sided test at the 5% level if the true mean and standard deviation of the DBP difference are the same as in the pilot study?
Hypertension
A pilot study of a new antihypertensive agent is performed for the purpose of planning a larger study. Five patients who have a mean DBP of at least 95 mm Hg are recruited for the study and are kept on the agent for 1 month. After 1 month the observed mean decline in DBP in these five patients is 4.8 mm Hg with a standard deviation of 9 mm Hg.
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