Codeine, C 18 H 21 O 3 N, is an opiate, has analgesic and antidiarrheal properties, and

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Codeine, C18H21O3N, is an opiate, has analgesic and antidiarrheal properties, and is widely used. In water, codeine is a weak base. A handbook gives pKa = 6.05 for protonated codeine, C18H21O3NH+. Write the reaction for C18H21O3NH+ and calculate pKb for codeine.

H C H HO  Codeine N-CH3

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General Chemistry Principles And Modern Applications

ISBN: 9780132931281

11th Edition

Authors: Ralph Petrucci, Jeffry Madura, F. Herring, Carey Bissonnette

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