In a 2018 study, researchers investigated the effect of the drug alteplase in the treatment of stroke
Question:
In a 2018 study, researchers investigated the effect of the drug alteplase in the treatment of stroke patients (Thomalla et al. 2018). Patients were randomly assigned to receive intravenous alteplase or a placebo. The patients’ neurological function was assessed 90 days after treatment. Of the 246 patients who received alteplase, 131 had a positive neurological outcome. Of the 244 patients who received a placebo, 102 had a positive neurological outcome.
a. Was this an observational study or a controlled experiment? Explain.
b. Find the percentage in each group that had a positive neurological outcome 90 days after treatment.
c. Researchers performed a test to determine if there was a significant difference in the proportion of positive neurological outcomes between the treatment and control groups. The p-value for the test is 0.003. Based on a 0.05 significance level, choose the correct conclusion:
i. Researchers have shown that alteplase may be an effective treatment for stroke patients.
ii. Researchers have not shown that alteplase may be an effective treatment for stroke patients.
Step by Step Answer:
Introductory Statistics Exploring The World Through Data
ISBN: 9780135163146
3rd Edition
Authors: Robert Gould, Rebecca Wong, Colleen N. Ryan