Describe the function of the PTEN phosphatase in the PI-3 kinase signaling pathway. Why is a loss-of-function

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Describe the function of the PTEN phosphatase in the PI-3 kinase signaling pathway. Why is a loss-of-function mutation in PTEN cancer promoting? Predict the effect of constitutively active PTEN on cell growth and survival.

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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Question Posted: Apr 17, 2018 05:32 AM

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Describe the function of the PTEN phosphatase in the PI-3 kinase signaling pathway. Why is a loss-of-function

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PTEN phosphatase removes the 3phosphate from PI 345triphosphate th...View the full answer

Molecular Cell Biology

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