Even though GRB2 lacks intrinsic enzymatic activity, it is an essential component of the epidermal growth factor
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Even though GRB2 lacks intrinsic enzymatic activity, it is an essential component of the epidermal growth factor (EGF) signaling pathway that activates MAP kinase. What is the function of GRB2? What role do the SH2 and SH3 domains play in the function of GRB2? Many other signaling proteins pm~ess SH2 domains. What determines the specificity of SH2 interactions with other molecules?
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GRB2 serves as an adapter molecule that contains b...View the full answer
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Related Book For 
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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