Examine the multipass transmembrane protein shown in Figure Q123. What would you predict would be the effect

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Examine the multipass transmembrane protein shown in Figure Q12–3. What would you predict would be the effect of converting the first hydrophobic transmembrane segment to a hydrophilic segment? Sketch the arrangement of the modified protein in the ER membrane.


Figure Q12-3

COOH 1 3 CYTOSOL ER LUMEN 2 4 6 NH2

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Molecular Biology Of The Cell

ISBN: 9780815344322

6th Edition

Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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