Explain why loss-of-function hedgehog and smoothened mutations yield the same phenotype but a loss-of-function patched mutation yields

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Explain why loss-of-function hedgehog and smoothened mutations yield the same phenotype but a loss-of-function patched mutation yields the opposite phenotype in flies.

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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Question Posted: Apr 17, 2018 05:34 AM

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Explain why loss-of-function hedgehog and smoothened mutations yield the same phenotype but a loss-of-function patched mutation yields

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Hedgehog Hh protein binding to the Patched receptor relieves its inhibition of Smoothened d...View the full answer

Molecular Cell Biology

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