Although oxirane (oxacyclopropane) and oxetane (oxacyclobutane) react with Grignard and organolithium reagents to form alcohols, tetrahydrofuran (oxacyclopentane)
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Although oxirane (oxacyclopropane) and oxetane (oxacyclobutane) react with Grignard and organolithium reagents to form alcohols, tetrahydrofuran (oxacyclopentane) is so unreactive that it can be used as the solvent in which these organometallic compounds are prepared. Explain the difference in reactivity of these oxygen heterocycles.
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Related Book For
Organic Chemistry
ISBN: 978-1118133576
11th edition
Authors: Graham Solomons, Craig Fryhle, Scott Snyder
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