Complete the reactions given in Fig. P27.70 assuming the amino acid residue is part of a peptide
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Complete the reactions given in Fig. P27.70 assuming the amino acid residue is part of a peptide in aqueous solution and is at neither the amino nor the carboxy terminus.
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(a) lysine residue + H₂C=O + NaCNBH3 (excess of both) (b) (c) lysine residue + succinic anhydride cysteine residue + NH pH 8 maleimide pH > 5 pH 9 (a conjugate-addition product)
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a b This is a reductive amination of formaldehyde by the amino group of the lysine residue Because e...View the full answer
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