Using abbreviated structures like the ones in Eq. 25.9a, give a curved-arrow mechanism for the reduction of mevaldehyde shown in Eq. 25.9b.

Transcribed Image Text:

protein (CH₂)-N-H- protonated lysine residue of the enzyme hydride transfer H mevaldehyde H H protein (CH₂), N-H- H H/H :O: :O: H protein H₂C H protein H₂C, R NADPH -CoA NH₂ R' NADP+ NH₂ protonated histidine residue of the enzyme :N H protein(CH₂)-N- -H H-S-COA H H H R TG H NH₂ R NADP+ protein H₂C -COA :N-H (25.9a)