Do you think that using a significance level of ???? = 0.05 is appropriate for all experiments?

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Do you think that using a significance level of ???? = 0.05 is appropriate for all experiments? In the early stages of research and development work, is there a lot of harm in identifying a factor as important when it really isn’t? Would that seem to justify higher levels of significance such as

???? = 0.10 or perhaps even ???? = 0.15 in some situations?

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