Lew (2007) presents the data from an experiment to determine whether cultured cells respond to two drugs. The experiment was conducted using a stable cell line plated onto Petri dishes, with each experimental run in-

volving assays of responses in three Petri dishes: one treated with drug 1, one treated with drug 2, and one untreated serving as a control. The data are shown in the table below:

(a) Analyze the data as if it came from a completely randomized design using the model yij = +i +ij . Is there a signicant dierence between the treatment groups?

(b) Analyze the data as an RCB design, where experiment number repre-
sents a blocking factor.

(c) Is there any dierence in the results you obtain in

(a) and (b)? If so explain what may be the cause of the dierence in the results and which method would you recommend?

Transcribed Image Text:

Control Drug 1 Drug 2 Experiment 1 1147 1169 1009 Experiment 2 1273 1323 1260 Experiment 3 1216 1276 1143 Experiment 4 1046 1240 1099 Experiment 5 1108 1432 1385 Experiment 6 1265 1562 1164