The effect estimates from a 24 factorial design are as follows: ABCD = −1.5138, ABC = −1.2661, ABD =

−0.9852, ACD = −0.7566, BCD = −0.4842, CD = −0.0795, BD = −0.0793, AD = 0.5988, BC = 0.9216, AC = 1.1616, AB = 1.3266, D = 4.6744, C = 5.1458, B = 8.2469, and A =

12.7151. Are you comfortable with the conclusions that all main effects are active?