The effect estimates from a 24 factorial experiment are listed here. Are any of the effects significant?

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The effect estimates from a 24 factorial experiment are listed here. Are any of the effects significant? ABCD =

−2.5251, BCD = 4.4054, ACD = −0.4932, ABD = −5.0842, ABC = −5.7696, CD = 4.6707, BD = −4.6620, BC =

−0.7982, AD = −1.6564, AC = 1.1109, AB = −10.5229, D = −6.0275, C = −8.2045, B = −6.5304, and A = −0.7914.

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