Suppose that the hypothesis mentioned in the previous question is correct and that gene A is actively

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Suppose that the hypothesis mentioned in the previous question is correct and that gene A is actively transcribed in liver cells, whereas gene B is actively transcribed in brain cells. The researcher now extracts equivalent amounts of chromatin from liver and brain tissues and treats these extracts separately with DNase I for a limited period of time. If the DNA that remains after the treatments is then fractionated by gel electrophoresis, transferred to a membrane by Southern blotting, and hybridized with a radioactively labeled probe specific for gene A, which sample (liver or brain) will be expected to show the greater signal on the autoradiogram? Explain your answer.

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Principles of Genetics

ISBN: 978-1119142287

7th edition

Authors: D. Peter Snustad, Michael J. Simmons

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