1) How does iodine deficiency affect the histology of the thyroid gland? What happened to the size of the colloid? Explain.

2) How would iodine deficiency affect the levels of the following? Use up and down arrows.

             Thyroglobulin ____         T3 ____         T4 ____

3) How would iodine deficiency affect the response of target tissues to T3 and T4 (Thyroid hormone)?

     increase  /  decrease  /  normal

4) A patient is diagnosed with follicular thyroid carcinoma (an overgrowth of follicle cells).  Would you expect the thyroid gland in this patient to be bigger, smaller, or the same as normal? Explain…