1) Hormone pathologies often manifest with elevated or lower hormones. The underlying cause may differ. What symptoms would be associated with hyperthyroidism? 

2) Autoimmune disease in which auto-antibodies stimulate the TSH receptor (TSHR) on the thyroid gland. How would this affect levels of TRH, TSH, and TH?  Draw out the H-P-T axis to illustrate changes in each hormone.

3) What symptoms would be associated with hypothyroidism?

4) How could this disease be treated? When the thyroid cells are destroyed, they cannot make hormones anymore and TH replacement needs to be given.