1.The following data was collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound was compared against a placebo. After treatment for 5 days with the new compound or placebo, the extent of wound healing was measured and the data are shown below.

Percent Wound Healing

Treatment 0-25% 26-50% 51-75% 76-100%

New Compound (n=125) 15 37 32 41

Placebo (n=125) 36 45 34 10

Is there a difference in the extent of wound healing by treatment? (Hint: Are treatment and the percent wound healing independent?)Run the appropriate test at a 5% level of significance.

Use the data in Problem #1 and pool the data across the treatments into one sample of size n=250. Use the pooled data to test whether the distribution of the percent wound healing is approximately normal. Specifically, use the following distribution: 30%, 40%, 20% and 10% anda=0.05 to run the appropriate test.

Percent Wound Healing

Treatment 0-25% 26-50% 51-75% 76-100% Total

Number of Patients 51 82 66 51 250