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3 Pe Home Insert egular (Bo $ 11 BIUaA v Q Clostridium difficile Log Number of Microorganisms/ g of stool Bacteroides Prevotella 10 Lecture 11:
3 Pe Home Insert egular (Bo $ 11 BIUaA v Q Clostridium difficile Log Number of Microorganisms/ g of stool Bacteroides Prevotella 10 Lecture 11: Host-Microbe Interactions In-class activity and bonus assignment Read the case study described, review the data figures included and answer the questions that follow. N Case Study: The study (as part of a larger clinical trial) includes 89 patients with Clostridium difficle infections (CDI), half of whom are randomly assigned to vancomycin treatment and half to fidaxomicin treatment. Antibiotics are administered for 10 days, and the patients are followed for several weeks. Dr. Rivera's research team collects fecal samples from the study participants periodically throughout the approximately 40-day trial. Fecal samples from 10 vancomycin-treated patients, 10 fidaxomicin-treated patients, and 10 healthy controls are analyzed to evaluate the effects of antibiotic treatment on the microbiome. Since each microbial group has a unique DNA sequence, the team quantifies
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