7. For those drugs that need to be applied with dissolution sustained system, what are their original properties? A. Low aqueous solubility and slow dissolution rate B. High aqueous solubility and slow dissolution rate C. Low aqueous solubility and fast dissolution rate D. High aqueous solubility and fast dissolution rate E. Gaseous state in room temperature with low aqueous solubility 8. Which of the following drug injection methods does involve perpendicularly inserting needle to the patient's body? A. Intramuscular injection B. Intravenous injection C. Subcutaneous injection D. Intradermal injection E. None of the above 9. Which of the following proteins is NOT commonly bound with drug in the bloodstream? A. Albumins B. Globulins C. Fibrinogens D. Antibodies E. None of the above 10. Which of the following events cannot increase the bioavailability of a drug? A. Patients suffer from cirrhosis B. Patients suffer from diarrhea C. Switch to intravenous injection from oral administration D. Switch to sustained-release formulations E. Switch to formulation with carriers 11. If the AUC for an oral dose of a drug administrated by tablet is 7.1 mcg/ml and the IV dose is 20.3 mcg/ml. What is the bioavailability of the oral dorse of the drug? (Correct to 2 significant figures.) A. 33% B. 34% C. 35% D. 36% E. 37% 12. For the drugs that are with low molecular weight and hydrophilic, which compartment will be most likely to be distributed? A. Blood plasma B. Extracellular fluid C. Organ or tissue surface D. Intracellular fluid E. Nucleus of cells