97. Type of ring structures present in the structure of Alprazolam?
a) Triazole
b) Benzene
c) Diazepine
d) All of the above

98. Correct sequence for the True/False for the physiochemical properties of the drug
solifenacin?
I. Molecular weight is 308.8 gm/mol
II. Produces crystals from ethylacetate
III. Melting point is between 228-229°C
IV. Diazepine ring is present
a) TFTF

b) TTTT
c) FFFF
d)FFFT

99. Binding of Diazepam with acetylcholine muscarinic receptors results in?
a) agonizing effect on muscarinic receptors
b) Antagonizing effect on muscarinic receptors
c) Do not produce any significant effect
d) Do not bind with muscarinic receptor

100. Therapeutic use of drug Diazepam is/are?
a) Treatment of Acute alcohol withdrawal
b) Treatment of seizures
c) Treatment of anxiety
d) All of the above

101. Which amongst the following are the correct statements with respect to the SAR of drug
Diazepam?
I. Ring A should include an aromatic or heteroaromatic ring for binding with 5-phenyl-1,4-
benzodiazepin-2-one derivatives.
II. An electronegative group at 7-position of the ring A increases the functional anxiolytic
activity.
III. Substitutions at 6, 8 or 9 position with electronegative group on ring A will decrease the
functional anxiolytic activity.
IV. When Heterocycles used as ring A, drug shows poor pharmacological activity.
a) I, IV
b) I, II, IV
c) I, II, III, IV
d) II, III, IV