A clinical trial is planned to compare an experimental medication designed to lower blood pressure to a placebo. Before starting the trial, a pilot study is conducted involving 7 participants. The objective of the study is to assess how systolic blood pressure changes over time untreated. Systolic blood pressures are measured at baseline and again 4 weeks later Is there a statistically significant difference in blood pressures over time? Run the test at a 5% level of significance. 1) Write out the appropriate null hypothesis and the alternative hypothesis; 2) Calculate the test statistic (show your work); 3) Give your conclusion including a comparison to alpha or the critical value.

Baseline	120	145	130	160	152	143	126
4 Weeks	122	142	135	158	155	140	130