Question
A crossover study was conducted to investigate whether oat bran cereal helps to lower serum cholesterol levels in hypercholesterolemic males. Fourteen such individuals were randomly
A crossover study was conducted to investigate whether oat bran cereal helps to
lower serum cholesterol levels in hypercholesterolemic males. Fourteen such
individuals were randomly placed on a diet that included either oat bran or corn flakes;
after two weeks, their low-density lipoprotein (LDL) cholesterol levels were recorded.
Each man was then switched to the alternative diet. After a second two-week period, the
LDL cholesterol level of each individual was again recorded.
The data from this study are shown below.
Subject LDL (mmol/l)
Corn Flakes Oat Bran
1 5.61 3.84
2 5.42 5.57
3 5.40 5.85
4 4.54 4.80
5 3.98 3.68
6 3.82 2.96
7 5.01 3.41
8 4.64 3.72
9 3.80 3.49
10 4.06 3.84
11 5.35 5.26
12 4.89 3.73
13 2.25 1.84
14 4.24 3.34
a. Are the two samples of data paired or independent?
b. What are the appropriate null and alternative hypotheses for a one-sided test?
c. Conduct the test at the 0.05 level of significance. What is the p-value?
d. What do you conclude?
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