A drug to reduce fever was given to a random sample of 7 patients who suffered from high fever. The temperature (in F) of each patient was measured just before the drug was administered and also measured four hours after the drug was administered. The data is presented in the table below. Suppose we want to test, at the 1% level of significance whether the drug is effective in lowering fever. Let?1denote the mean temperature of patients four hours after taking the drug and let?2denote the mean temperature of patients before taking the drug. Also let?D=?1??2. Assume all the assumptions of this test are satisfied. Answer the following questions.

Table Patient 2 3 4 5 6 7 Before 103.1 101.9 104.6 101.8 102.5 103.7 102.9 After 102.8 102.3 103.5 102.6 101.4 103.1 103.5Level of Soccer Arthritis Elite Semi-elite Non-elite Did not play Yes 25 26 196 12 No 34 73 402 54