A large number of articles have been published related to the research question (Does hydroxychloroquine or chloroquine help prevent COVID-19?). The following are a few examples of peer-reviewed publications in academic journals. Which of these studies provides the weakest evidence, according to the level of evidence in L02 Slide 12?

A.

(Barnabas et al., 2021)

B.

(Lewis et al., 2021)

C.

(Sen et al., 2020)

D.

(Smit et al., 2021)

E.

(Somberg, 2020)