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A proposed retrosynthesis for m - isobutylbenzenesulfonic acid ( 1 ) is shown in the scheme below. Answer the following questions with this retrosynthesis in
A proposed retrosynthesis for isobutylbenzenesulfonic acid is shown in the scheme below. Answer the following questions with this retrosynthesis in mind.
a Write out the forward synthesis for the above retrosynthetic scheme, including all necessary reagents and reaction conditions.
b Try to identify any problems with the proposed synthesis. There are two major issues. Describe them.
c Try to devise a better, alternate synthetic route that avoids the problems identified in
Design retrosynthetic analyses and forward syntheses for compounds starting from the appropriate phenol:
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