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A randomized trial was performed to evaluate the effectiveness of a new drug on controlling Type I diabetes in teenagers. A random sample of 150

A randomized trial was performed to evaluate the effectiveness of a new drug on controlling Type I diabetes in teenagers. A random sample of 150 patients were obtained from the pediatric diabetes clinic at Sick Kids in Toronto, Ontario; 75 were randomly assigned to the treatment group (new drug) and 75 were randomly assigned to the control group (existing drug). You may assume that basic factors such as validity of the inclusion criteria, blinding, etc. were performed appropriately.

Baseline information such as age and gender were collected and key outcomes of A1C level and number of hypoglycemic events were measured after four weeks. A1C levels indicate what percentage of your hemoglobin is coated with sugar (glycated). Higher A1C levels indicate poorer blood sugar control and a higher risk for diabetes complications. A hypoglycemic event occurs when the plasma glucose levels become too low; this is a common and adverse effect of diabetes therapy which has been shown to negatively impact on quality of life.

  1. Do the number of hypoglycemic events differ between the treatment and control groups? In other words, is there a statistically significant relationship between the number of hypoglycemic events and group (treatment and control)? Run the appropriate test at the 5% level of significance. ( Did a chi test , picture included)
  2. Is there a statistically significant difference in A1C levels between the treatment and control groups? Run the appropriate test at the 5% level of significance and decide on a 1-tail or 2-tail test. ( did T-test of independed)

Which varaibles are categorical and contunous

image text in transcribedimage text in transcribed
Independent Samples Test Levene's Test for Equality of Variances t-test for Equality of Means 95% Confidence Interval of the Mean Std. Error Difference F Sig. t df Sig. (2-tailed) Difference Difference Lower Upper A1C Equal variances 1.295 257 .305 148 761 1013 3319 -.5546 7573 assumed Equal variances not 305 146.416 .761 1013 3319 -.5546 assumed .7573 Independent Samples Effect Sizes Point 95% Confidence Interval Standardizera Estimate Lower Upper A1C Cohen's d 2.0326 050 -.270 370 Hedges' correction 2.0430 050 -.269 368 Glass's delta 2.1357 047 -.273 .367valid Missing Total N Percent N Percent N Percent group *hypo 150 100.0% 0 0.0% 150 100.0% group * hypo Crosstabulation Count hypo 0 1 2 Total group 0 13 35 27 75 33 25 17 75 Total 46 60 44 150 Chi-Square Tests Asymptotic Significance Value df (2-sided) Pearson Chi-Square 12.635 2 002 Likelihood Ratio 12.960 N 002 Linear-by-Linear 9.936 002 Association N of Valid Cases 150

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