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A semi - batch bio - reactor with the volumetric flowrates Fi ( in liters / hour ) for the inlet stream, has an initial
A semibatch bioreactor with the volumetric flowrates Fi in litershour for the inlet stream, has an initial liquid volume V L for the contents inside, which is changing since there is only Fi Assume that the density of all material is constant at gL There are no cells or product in the inlet stream. The reactor is well mixed. Substrate is present in the inlet stream. The inlet concentration of substrate is Sf gL constant Take the concentrations of substrate, cells and products inside the reactor as S X and P all varying with time all in gL The growth rate of the cells and products is defined as:rgX where the specific growth rate of the cells is given by m SKSS with maximum specific growth rate m as h and KS gL rPYPXrg where YPX Also, take YXS and YPS both as Fi can be taken as Lh and the steady state values of X S and P can all be taken as gL Derive a model for the reactor by doing the overall MB and component balances for the cell, substrate and products. Remember that the only variables in the system are V X P and S
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