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A spherical tablet loaded with medication is being tested for slow drug release. The tablet is held stationary in a moving fluid that stimulates
A spherical tablet loaded with medication is being tested for slow drug release. The tablet is held stationary in a moving fluid that stimulates blood flow. The Sherwood number for a laminar flow around the stationary sphere in liquid is: Sh= KL D DAB = (4.0+ 1.21. (ReSc)2/3)1/2 where K is the convective mass transfer in liquid [cm/s], and D the diameter of the sphere [cm]. The table below includes various physical quantities of the system: DAB diffusion 106 viscosity 0.04 Diameter 0.5 Sc X of drug cm/s of fluid g/(cm s) of tablet cm = in fluid 104 Density 1.05 of fluid g/cm Drug 2.5 x solubility 10-4 in fluid mg/cm initial 3 Re loading mg= What is the convective mass transfer coefficient for this system [cm/s]? 3.81 66.8
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