Answer questions 1-5

Instructions: This quiz consists of 24 MC questions. You have 2 hours to complete this quiz and submit your solutions. Work individually! You may use your own formula sheets containing relevant handwritten notes, a standard or scientific calculator, and/or statistical software (e.g., SAS@, R). To receive full credit, you must show all your work. Good luck! Researchers conducted a study to examine the effects of the experimental anti-hypertensive agent GB2995 on diastolic blood pressure (DBP) among 75 patients with moderate to severe hypertension in four study centers. They were interested in comparing 12 weeks of treatment using (1) GB2995 as the sole therapy (SOLE) versus (2) GB2995 in combination with a stable dose of a marketed calcium-channel blocker (COMB) when administered to patients with moderate to severe hypertension. The primary analysis focused on a comparison of the mean change in DBP between the two treatment groups, adjusted for the patient's age (AGE) and severity of hypertension at study entry (BPDIAO). Note that the response to be analyzed is the change (or difference) in the DBP. Also, note that baseline severity is the average DBP obtained on three pre-study visits. Using a 0.05 significance level and the given computer output, you now need to test the claim that the patients in the four study centers have a different mean change in DBP by answering the questions that follow. Note that the change in DBP, baseline severity, and age can be considered continuous here, whereas the study center and treatment group are categorical. For questions 1-5, examine the computer output of the five different models provided for you in the separate packet labeled SAS Output #1-SAS Output #5. Match the output with the most appropriate analysis. You may select each letter (method) more than once, once or not at all. (1 point each) 1. SAS Output #1 a. ANCOVA 2. SAS Output #2 b. Multiple linear regression 3. SAS Output #3 c. One-way ANOVA 4. SAS Output #4 d. Two-way ANOVA without an interaction 5. SAS Output #5 e. Two-way ANOVA with an interaction