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Apply the principles of retrosynthetic analysis to develop a synthesis of alcohol 11 from pentane-1,5-diol 12. Show all disconnections, synthons and functional group interconversions (FGI's)
Apply the principles of retrosynthetic analysis to develop a synthesis of alcohol 11 from pentane-1,5-diol 12. Show all disconnections, synthons and functional group interconversions (FGI's) in the retrosynthetic direction. Suggest reagents for the forward synthesis and comment on any selectivity issues that might arise. Several steps are required; include all working and partial solutions.
OTBDMS HO COTBDMS HO HO. 10 11 12
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