ASAP!!

4. In humans, the antibiotic Ceftriaxone has the mean values for the apparent volume of distribution 300L and total clearance CL=14L/h and t1/2=8h. Salmonella infection is susuceptible to Ceftriaxone at concntration above 5ug/mL and patient gets overdosed at the levels above 80ug/L. Calculate an IV dose ad infusion rate that provides steady-state level of 30ug/mL in human. b)The doctor decides to give a dose of 12mg and started a constatnt infusion at the same R0 calculated . Ceftriaxone is eliminated as unchanges in the urine and the drug concentrations were recorded as ; a) Compute the Vd for patient (10pts) b) Compute the CL (10pts)