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As a technician in a large pharmaceutical research firm, you need to produce 250. mL of a potassium dihydrogen phosphate buffer solution of pH =
As a technician in a large pharmaceutical research firm, you need to produce 250. mL of a potassium dihydrogen phosphate buffer solution of pH = 6.94. The pKa of H2PO4− is 7.21. You have the following supplies: 2.00 L of 1.00 M KH2PO4 stock solution, 1.50 L of 1.00 M K2HPO4 stock solution, and a carboy of pure distilled H2O . How much 1.00 M KH2PO4 will you need to make this solution? (Assume additive volumes.)
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